Hi all! Happy New Year! May 2009 be the year that there are no cancer scares for me or for you or your loved ones! The good news: I’m feeling better overall than I have for years, so take heart. Continue reading
Category Archives: tamoxifen
Okay, minor suckage for the day – tamoxifen and I are just NOT the best of friends. I’ve bailed on it again, and now, 5 days later, I’m beginning to feel SOOO much better! Continue reading
Just got back from my 3-month medical oncology checkup. My onc. was surprisingly accepting of the fact that I decided to take a short tamoxifen break while I’m finishing up rads. I was afraid he’d be mad, but he wasn’t at all. Whew. Not only that, he offered to do the CYP2D6 testing to see if I metabolize tamoxifen AND he offered to do hormone testing as well. Continue reading
I actually feel quite insane given what I rationally know to be helpful about tamoxifen (it increases my survival chances as much as chemo), but I seem to be deciding not to take it. A temporary drug holiday, until I’m recovered from rads. I’ve been beyond tired, what with a cold, rads fatigue and tamoxifen general yuckiness. And when I go to take that tamoxifen pill? You know how it is when you just aren’t interested in a certain food? Continue reading
I first started taking wellbutrin in mid-2006, because I had overwhelming fatigue. Go figure, I had cancer. (A fact which we wouldn’t discover until 8 months later, but enough about that. For now.) I told my HMO at the time that I wasn’t depressed, I just felt very tired. So they of course put me on a series of anti-depressants, most of which did nothing, until we tried wellbutrin, which can act as a stimulant. Even at very small doses, it helped.
Thanks to the heads up from breastcancer.org forum members, I asked my doc. (the one who prescribes wellbutrin, not my oncologist) about the info. I’d read on wellbutrin inhibiting tamoxifen.
She looked it up, and indeed there is a “cautionary” warning about its interaction with CYP2D6-metabolized drugs such as tamoxifen. It’s not a black-box warning, and it’s even not a strong warning as it doesn’t require monitoring. But still, she said it does compete with tamoxifen for metabolizing, so, since tamoxifen has such an important role in protecting me from cancer right now, her advice was to “Stop the wellbutrin. Now.” Continue reading